Subarachnoid haemorrhage in pseudoxanthoma elasticum.

Introduction Pseudoxanthoma elasticum (PXE) is a rare heritable disorder of the connective tissue. Up to 1964, approximately 400 cases had been reported (Suerig and Siefert, 1964). The lesion involves mainly the skin, the eyes and the cardiovascular system, giving rise to diverse clinical manifestations. Most of the reports have highlighted the association of cutaneous changes with angioid streaks in the retina, gastro-intestinal haemorrhage and cardiovascular involvement. The neurological manifestations of PXE have not been reported as commonly. We report a patient with PXE who presented with subarachnoid haemorrhage.